United Airlines flight UA 543: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Mon-Fri,Sun 06:35 Newark Liberty, New York (EWR) A 09:47 Santa Ana (SNA)
UA 543 Non-stop Boeing 737 MAX 8 (7M8) 6:12 Effective 2026-01-06 through 2026-02-03
Sat 06:35 Newark Liberty, New York (EWR) C 09:47 Santa Ana (SNA)
UA 543 Non-stop Boeing 737 MAX 8 (7M8) 6:12 Effective 2026-01-10 through 2026-02-07
Mon-Fri,Sun 06:35 Newark Liberty, New York (EWR) A 09:47 Santa Ana (SNA)
UA 543 Non-stop Boeing 737 MAX 8 (7M8) 6:12 Effective 2026-02-05 through 2026-02-11
Sun 06:51 Buffalo (BUF) 07:54 Chicago O'Hare (ORD) 1
UA 543 Non-stop Airbus A319 (319) 2:03 Effective 2026-03-08 through 2026-03-22
Daily 07:00 Buffalo (BUF) 08:00 Chicago O'Hare (ORD) 1
UA 543 Non-stop Airbus A319 (319) 2:00 Effective 2026-02-12 through 2026-03-07
Mon-Sat 07:00 Buffalo (BUF) 08:00 Chicago O'Hare (ORD) 1
UA 543 Non-stop Airbus A319 (319) 2:00 Effective 2026-03-09 through 2026-03-28
Daily 07:00 Buffalo (BUF) 07:57 Chicago O'Hare (ORD) 1
UA 543 Non-stop Boeing 737-700 (73G) 1:57 Effective 2026-03-29 through 2026-04-29
Daily 07:00 Buffalo (BUF) 07:48 Chicago O'Hare (ORD) 1
UA 543 Non-stop Boeing 737-700 (73G) 1:48 Effective 2026-04-30 through 2026-05-20
Daily 07:00 Buffalo (BUF) 07:48 Chicago O'Hare (ORD) 1
UA 543 Non-stop Boeing 737 MAX 8 (7M8) 1:48 Effective from 2026-05-21
Daily 10:35 Chicago O'Hare (ORD) 1 13:28 San Francisco (SFO) 3
UA 543 Non-stop Boeing 757-300 (753) 4:53 Effective 2026-04-30 through 2026-05-20
Daily 10:45 Chicago O'Hare (ORD) 1 13:42 San Francisco (SFO) 3
UA 543 Non-stop Airbus A321neo (32Q) 4:57 Effective 2026-03-29 through 2026-04-29
Daily 10:45 Chicago O'Hare (ORD) 1 13:42 San Francisco (SFO) 3
UA 543 Non-stop Airbus A321neo (32Q) 4:57 Effective from 2026-10-25
Daily 10:47 Chicago O'Hare (ORD) 1 13:35 San Francisco (SFO) 3
UA 543 Non-stop Airbus A321neo (32Q) 4:48 Effective 2026-05-21 through 2026-10-24
Mon-Fri,Sun 11:00 Chicago O'Hare (ORD) 1 14:02 San Francisco (SFO) 3
UA 543 Non-stop Boeing 737-900 (739) 5:02 Effective 2026-03-05 through 2026-03-27
Sat 11:00 Chicago O'Hare (ORD) 1 14:02 San Francisco (SFO) 3
UA 543 Non-stop Boeing 737 MAX 9 (7M9) 5:02 Effective 2026-03-07 through 2026-03-21
Sat 11:00 Chicago O'Hare (ORD) 1 14:02 San Francisco (SFO) 3
UA 543 Non-stop Boeing 737-900 (739) 5:02 Operates only on 2026-03-28
Wed 17:15 Missoula (MSO) 19:24 Denver (DEN)
UA 543 Non-stop Boeing 737-800 (738) 2:09 Operates only on 2026-02-04
Daily 19:25 Denver (DEN) 20:49 Palm Springs (PSP)
UA 543 Non-stop Airbus A320 (320) 2:24 Valid until 2026-01-04
Mon 19:25 Denver (DEN) 20:49 Palm Springs (PSP)
UA 543 Non-stop Boeing 737-900 (739) 2:24 Operates only on 2026-01-05
Non-Direct Flights:
Sun 06:51 Buffalo (BUF) 14:02 San Francisco (SFO) 3
UA 543 1-stop Airbus A319 (319) 10:11 Effective 2026-03-08 through 2026-03-22
Mon-Sat 07:00 Buffalo (BUF) 14:02 San Francisco (SFO) 3
UA 543 1-stop Airbus A319 (319) 10:02 Effective 2026-03-05 through 2026-03-28
Daily 07:00 Buffalo (BUF) 13:42 San Francisco (SFO) 3
UA 543 1-stop Boeing 737-700 (73G) 9:42 Effective 2026-03-29 through 2026-04-29
Daily 07:00 Buffalo (BUF) 13:28 San Francisco (SFO) 3
UA 543 1-stop Boeing 737-700 (73G) 9:28 Effective 2026-04-30 through 2026-05-20
Daily 07:00 Buffalo (BUF) 13:35 San Francisco (SFO) 3
UA 543 1-stop Boeing 737 MAX 8 (7M8) 9:35 Effective 2026-05-21 through 2026-10-24
Daily 07:00 Buffalo (BUF) 13:42 San Francisco (SFO) 3
UA 543 1-stop Boeing 737 MAX 8 (7M8) 9:42 Effective from 2026-10-25
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This flight number is listed as serving the following routes:


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United Airlines flight UA 543: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
United Airlines UA543
06:35
Newark Liberty, New York (EWR) A

09:47
Santa Ana (SNA)
Effective 2026-01-06 through 2026-02-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 6:12, non-stop
Boeing 737 MAX 8 (7M8)
Direct Flights:
United Airlines UA543
06:35
Newark Liberty, New York (EWR) C

09:47
Santa Ana (SNA)
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 6:12, non-stop
Boeing 737 MAX 8 (7M8)
Direct Flights:
United Airlines UA543
06:35
Newark Liberty, New York (EWR) A

09:47
Santa Ana (SNA)
Effective 2026-02-05 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 6:12, non-stop
Boeing 737 MAX 8 (7M8)
Direct Flights:
United Airlines UA543
06:51
Buffalo (BUF)

07:54
Chicago O'Hare (ORD) 1
Effective 2026-03-08 through 2026-03-22
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:03, non-stop
Airbus A319 (319)
Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

08:00
Chicago O'Hare (ORD) 1
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:00, non-stop
Airbus A319 (319)
Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

08:00
Chicago O'Hare (ORD) 1
Effective 2026-03-09 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 2:00, non-stop
Airbus A319 (319)
Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

07:57
Chicago O'Hare (ORD) 1
Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Boeing 737-700 (73G)
Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

07:48
Chicago O'Hare (ORD) 1
Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Boeing 737-700 (73G)
Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

07:48
Chicago O'Hare (ORD) 1
Effective from 2026-05-21
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Boeing 737 MAX 8 (7M8)
Direct Flights:
United Airlines UA543
10:35
Chicago O'Hare (ORD) 1

13:28
San Francisco (SFO) 3
Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:53, non-stop
Boeing 757-300 (753)
Direct Flights:
United Airlines UA543
10:45
Chicago O'Hare (ORD) 1

13:42
San Francisco (SFO) 3
Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:57, non-stop
Airbus A321neo (32Q)
Direct Flights:
United Airlines UA543
10:45
Chicago O'Hare (ORD) 1

13:42
San Francisco (SFO) 3
Effective from 2026-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:57, non-stop
Airbus A321neo (32Q)
Direct Flights:
United Airlines UA543
10:47
Chicago O'Hare (ORD) 1

13:35
San Francisco (SFO) 3
Effective 2026-05-21 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:48, non-stop
Airbus A321neo (32Q)
Direct Flights:
United Airlines UA543
11:00
Chicago O'Hare (ORD) 1

14:02
San Francisco (SFO) 3
Effective 2026-03-05 through 2026-03-27
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 5:02, non-stop
Boeing 737-900 (739)
Direct Flights:
United Airlines UA543
11:00
Chicago O'Hare (ORD) 1

14:02
San Francisco (SFO) 3
Effective 2026-03-07 through 2026-03-21
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 5:02, non-stop
Boeing 737 MAX 9 (7M9)
Direct Flights:
United Airlines UA543
11:00
Chicago O'Hare (ORD) 1

14:02
San Francisco (SFO) 3
Operates only on 2026-03-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 5:02, non-stop
Boeing 737-900 (739)
Direct Flights:
United Airlines UA543
17:15
Missoula (MSO)

19:24
Denver (DEN)
Operates only on 2026-02-04
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:09, non-stop
Boeing 737-800 (738)
Direct Flights:
United Airlines UA543
19:25
Denver (DEN)

20:49
Palm Springs (PSP)
Valid until 2026-01-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:24, non-stop
Airbus A320 (320)
Direct Flights:
United Airlines UA543
19:25
Denver (DEN)

20:49
Palm Springs (PSP)
Operates only on 2026-01-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:24, non-stop
Boeing 737-900 (739)
Non-Direct Flights:
United Airlines UA543
06:51
Buffalo (BUF)

14:02
San Francisco (SFO) 3
Effective 2026-03-08 through 2026-03-22
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 10:11, 1-stop
Airbus A319 (319)
Non-Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

14:02
San Francisco (SFO) 3
Effective 2026-03-05 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 10:02, 1-stop
Airbus A319 (319)
Non-Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

13:42
San Francisco (SFO) 3
Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 9:42, 1-stop
Boeing 737-700 (73G)
Non-Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

13:28
San Francisco (SFO) 3
Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 9:28, 1-stop
Boeing 737-700 (73G)
Non-Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

13:35
San Francisco (SFO) 3
Effective 2026-05-21 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 9:35, 1-stop
Boeing 737 MAX 8 (7M8)
Non-Direct Flights:
United Airlines UA543
07:00
Buffalo (BUF)

13:42
San Francisco (SFO) 3
Effective from 2026-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 9:42, 1-stop
Boeing 737 MAX 8 (7M8)
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This flight number is listed as serving the following routes:
  • Buffalo (BUF) - Chicago O'Hare (ORD)
  • Buffalo (BUF) - San Francisco (SFO)
  • Chicago O'Hare (ORD) - San Francisco (SFO)
  • Denver (DEN) - Palm Springs (PSP)
  • Missoula (MSO) - Denver (DEN)
  • Newark Liberty, New York (EWR) - Santa Ana (SNA)
All United Airlines flights
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